St. John's wort does not appear to improve the symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and teens in comparison with a placebo, according to an article released on June 10, 2008 in JAMA.

Hypericum perforatum, also called St. John's wort, is a flowering plant often used in alternative medicine to treat depression. Many studies have been used to test its efficacy for this and other indications. Its active chemical is called hypercin, and some of its efficacy is attributed to this substance.

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